Back to Store

Pathogenic

Pathogenic cover art
Developer
Aberrant Labs
Publisher
Slug Disco
Released
Jul 16, 2026
Steam reviews
93% of players recommend it, from 4,571 reviews — Steam calls that “Very Positive”
Tags
ActionIndieRPG
View on Steam

On Linux, Steam Deck and Steam Machine

Native LinuxDeck VerifiedSteam Machine: VerifiedSteamOS Compatible

Ships a native Linux build on Steam — no Proton needed. Valve rates it Deck Verified.

Valve rates it Verified on Steam Machine. Valve marks it SteamOS Compatible.

Native build: Steam · Proton tier: ProtonDB · Deck rating: Valve · Steam Machine, Steam Frame and SteamOS ratings: Valve · Compare 2,053 games · Every game Valve rated for Steam Machine

Check my library

See this for every game you own. Paste a Steam profile: no account, nothing to install.

About this game

The developer's description, from the game's Steam store page.

CELLULAR COMBAT EVOLVED

In Pathogenic, you are the disease. Experience a visceral 2D roguelike twin-stick shooter where you play as a lone parasite fighting a desperate war against the immune system. Your goal is simple: infect and conquer your human host.

To survive, you must adapt. Hunt down enemy cells, rip out their organelles, and graft them onto your own body. Evolve from a simple cell into a complex engine of destruction. Create powerful, game-breaking builds and become the ultimate pathogen.

CREATE YOUR OWN PATHOGEN

Loot, graft, and assemble your parasite from dozens of unique organelles. Combine flagella for movement, mitochondria for power, secretors for ranged attacks, and spikes for melee combat. Chain organelle effects and discover powerful synergies to build an unstoppable disease vector.

FIGHT THE IMMUNE SYSTEM

Battle a diverse roster of enemies, from basic immune cells like macrophages and T cells to rival parasites such as tapeworms or protozoa. Formidable bosses are lurking deep within the host's organs.

METAPROGRESSION

Collect plasmid fragments to permanently upgrade your parasite's plasmid tree between runs. Each parasite will have it's own upgrade tree allowing for a range of builds to suit your preferred playstyle.

EXPLORE A MICROSCOPIC WORLD

Navigate the procedurally generated organic landscape of the human body. Travel through distinct biomes like the branching pathways of the lungs, the pulsating chambers of the heart, and the complex neural network of the brain.

FEEL THE ORGANIC ACTION

Our detailed, colorful world is powered by a soft-body physics simulation, giving every cell, enemy, and projectile a uniquely satisfying organic feel. The combination of hand-crafted design and procedural generation ensures endless variety - each run offers a fresh and challenging gameplay experience.

JOIN OUR COMMUNITY ON DISCORD

System requirements

As Steam lists them.

Windows

Minimum

Requires a 64-bit processor and operating system
OS
Windows 10 64-bit
Processor
Intel Core i5-6500 / AMD Ryzen 3 1200 or equivalent
Memory
8 GB RAM
Graphics
GeForce GTX 1050 / Radeon RX 560
DirectX
Version 12
Storage
2 GB available space

Recommended

Requires a 64-bit processor and operating system
macOS

Minimum

OS
macOS 13
Processor
Apple M1 or Intel Core M
Memory
8 GB RAM
Storage
2 GB available space
SteamOS + Linux

Minimum

OS
SteamOS 3 / Ubuntu 22.04
Processor
Intel Core i5-6500 / AMD Ryzen 3 1200 or equivalent
Memory
2 GB RAM
Graphics
GeForce GTX 1050 / Radeon RX 560
Storage
2 GB available space

Downloadable content

Steam lists 1 item of downloadable content for this game.

News

What Pathogenic's studio and the outlets Valve syndicates on Steam have said recently.

More like this

Games in Sifter’s catalogue sharing the most Steam genres with this one.